Beads conjugated and tested in HeLa cells; inconclusive.
E2F4 Bead Test
Notes:
Mutations in E2F4 have been observed in CRC. PMID24100580: "...cancer associated E2F4 mutations enhance the capacity of CRC cells to grow without anchorage, conritbuting to tumor progression..."
Crucial role in action of tumor suppressor proteins (per uniprot)